Prefrontal dopamine in the dynamic processes of learning across lifetime. To facilitate age-specific adaptive action in a changing environment, how we learn changes not only as we grow, but also as we

Description

Prefrontal dopamine in the dynamic processes of learning across lifetime. To facilitate age-specific adaptive action in a changing environment, how we learn changes not only as we grow, but also as we age. However, the neurobiological processes in these age-related changes are poorly studied. This is a significant knowledge gap that needs to be addressed to promote healthy cognitive development and ageing. This research program aims to examine the contribution of prefrontal dopamine and its receptors D1 and D2 in associative learning and its inhibition at 9 distinct ages spanning development to ageing in male and female rats. The outcomes will provide a new neuroscientific framework to understand learning and memory throughout life, which will foster new research opportunities and inform our education and health.. Scheme: ARC Future Fellowships. Field: 5202 - Biological Psychology. Lead: Prof Jee Hyun Kim