Dynamics of calcitonin family receptor activation. Major life science challenges include how cells respond to their extracellular environment to mediate a biological response. This project seeks to el

Description

Dynamics of calcitonin family receptor activation. Major life science challenges include how cells respond to their extracellular environment to mediate a biological response. This project seeks to elucidate how biological signals essential to life are transmitted through receptors on the surface of our cells. This project seeks to directly enhance our understanding of how receptors respond to essential life molecules to control fundamental physiological responses, with anticipated future benefits for the pharmaceutical industry. The primary outcomes of this project will provide detailed mechanistic insights on how receptors bind their stimuli and how this results in in their activation to mediate fundamental signalling that is important for all living organisms.. Scheme: Discovery Projects. Field: 3214 - Pharmacology and Pharmaceutical Sciences. Lead: Dr Tracy Josephs