Rethinking lactate – from metabolic ‘poison’ to critical metabolic signal? This ambitious project aims to use a highly innovative approach to challenge the long-standing paradigm of lactate as a metab

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Rethinking lactate – from metabolic ‘poison’ to critical metabolic signal? This ambitious project aims to use a highly innovative approach to challenge the long-standing paradigm of lactate as a metabolic ‘poison’ and to discover new biological roles of lactate. The project expects to generate advanced and new knowledge about the effects of lactate as a metabolic signal that can communicate with cells. The expected outcomes should include significant new knowledge concerning the role of lactate in regulating skeletal muscle. This could provide significant long-term socioeconomic benefits for 1) the life sciences (the development of new therapies and drugs aimed at improving health), 2) agriculture (lactate strongly influences meat quality), and 3) sport (improving recovery and performance).. Scheme: Discovery Projects. Field: 4207 - Sports Science and Exercise. Lead: Prof David Bishop