How Does The Bladder Sense Danger? . This project aims to reveal the unique features of bladder-innervating sensory nerves that are necessary for detecting pathogenic infections. Combining electrophys

Description

How Does The Bladder Sense Danger? . This project aims to reveal the unique features of bladder-innervating sensory nerves that are necessary for detecting pathogenic infections. Combining electrophysiological sensory nerve recordings with cutting-edge spatial and single cell omic tools, this project will identify and characterise the nerves innervating the bladder that respond to harmful stimuli and initiate protective reflexes to restore bladder health. This project will advance sensory neuroscience by delivering a world-first functional and transcriptional view of the peripheral sensory pathways supporting bladder function. By fully understanding how the bladder senses its environment, this knowledge will accelerate future drug discovery for common bladder disorders.. Scheme: Discovery Projects. Field: 3209 - Neurosciences. Lead: Dr Luke Grundy