Harnessing glycomics to dissect virus-mosquito interaction and transmission. This project aims to investigate the role of carbohydrate molecules on viruses and mosquito cells in influencing infection,

Description

Harnessing glycomics to dissect virus-mosquito interaction and transmission. This project aims to investigate the role of carbohydrate molecules on viruses and mosquito cells in influencing infection, replication, and spread within mosquitos. How these interactions impact the transmission of mosquito-borne viruses will be examined. Using state-of-the-art spatial biology and glycomics, the project aims to uncover molecular mechanisms by which viruses interact with cell surface receptors, utilise mosquito host factors for replication, and spread within mosquito tissues, ultimately shaping transmission to mammalian hosts. This research should advance understanding of virus-mosquito biology, support antiviral development, and improve public health preparedness through better surveillance and mosquito control strategies.. Scheme: Discovery Early Career Researcher Award. Field: 3107 - Microbiology. Lead: Dr Xiang Liu