Novel regulators of immune cell development in the digestive tract. This study aims to better understand immune cell development, homeostatic maintenance and essential repair processes in the intestin

Description

Novel regulators of immune cell development in the digestive tract. This study aims to better understand immune cell development, homeostatic maintenance and essential repair processes in the intestine. This project aims to generate new knowledge of how immune cells of the intestine, known as gamma delta T cells, engage with intestinal barrier epithelial cells and endothelial cells to promote homeostasis and repair. Expected outcomes of this project will be the identification of new molecules for future drug and vaccine development to improve gut health in mammals. This could provide significant downstream benefits to the Australian population and livestock industry through improved protection against cancer and intestinal infections, as well as increased productivity.. Scheme: ARC Future Fellowships. Field: 3204 - Immunology. Lead: A/Prof Lisa Mielke