Synthesis and Applications of Shape-Shifting Molecules. Shape-shifting molecules have no permanent structure and exist in constant metamorphosis. This unique class of molecule has the potential to unl

Description

Synthesis and Applications of Shape-Shifting Molecules. Shape-shifting molecules have no permanent structure and exist in constant metamorphosis. This unique class of molecule has the potential to unlock applications in drug discovery, materials, and molecular devices. This project will expand and simply access to these molecules through a synthetic building block approach. From there we will prototype a range of concepts and applications spanning shape-shifting dimeric drugs, peptides, liquid crystals, and molecular devices. Expected outcomes include a synthetic platform which will greatly simply the preparation of shape-shifters to accelerate discovery, as well as developing design principles for future advanced applications.. Scheme: Discovery Projects. Field: 3405 - Organic Chemistry. Lead: Dr Thomas Fallon