Microbial gas metabolism in the mammalian gut: from enzymes to ecosystems. Hydrogen gas is one of the most central, but least understood, metabolites cycled in the gut. This fellowship will provide th

Description

Microbial gas metabolism in the mammalian gut: from enzymes to ecosystems. Hydrogen gas is one of the most central, but least understood, metabolites cycled in the gut. This fellowship will provide the first system-wide understanding of hydrogen production and consumption in the guts of both humans and ruminants. By uniquely synergising studies at the enzyme, cellular, and gut ecosystem scales, we will resolve the microbial and enzymatic mediators of hydrogen cycling, determine how they function at a molecular level, and demonstrate how they interact to shape gut processes. The project will provide wide-reaching benefits by increasing fundamental understanding of gut function, ecology, and biogeochemistry, and will guide efforts and develop partnerships to mitigate methane emissions from the livestock sector. . Scheme: ARC Future Fellowships. Field: 3107 - Microbiology. Lead: Prof Chris Greening