Defining cell communication and mechanics in tissue specific vasculature. This project aims to improve our understanding of the mechanical properties that regulate the organ-specificity of blood vesse

Description

Defining cell communication and mechanics in tissue specific vasculature. This project aims to improve our understanding of the mechanical properties that regulate the organ-specificity of blood vessels and their function. The endothelial cells lining blood vessels play a specialised role in the local physiology of their respective organs, however little is known about the fundamental biophysical events which trigger or characterise this function. This project expects to generate new knowledge in the area of developmental biology using collaborative, cutting-edge biomechanical techniques. In studying this process, the project should provide critical insights into how changes in cell and fluid mechanics are interpreted by, and consequently determine the identity and function of organ-specific endothelial cells.. Scheme: Discovery Projects. Field: 4003 - Biomedical Engineering. Lead: Prof Laura Bray