Molecular Functions of Nicotinamide Adenine Dinucleotide Metabolites. This project aims to investigate the functions of metabolites from the breakdown of nicotinamide adenine dinucleotide (NAD+), an e

Description

Molecular Functions of Nicotinamide Adenine Dinucleotide Metabolites. This project aims to investigate the functions of metabolites from the breakdown of nicotinamide adenine dinucleotide (NAD+), an essential molecule for all cellular life forms. These metabolites are likely to play important biological roles in bacteria, plants, and animals, especially in their immune systems. This project expects to determine the structure and function of these metabolites at the molecular level, filling a critical knowledge gap in NAD+-mediated signalling processes. Expected outcomes of this project include advanced knowledge of NAD+-mediated signalling and innate immunity pathways. This should provide significant commercial and economic benefits via the development of technologies against pathogens in plants and animals.. Scheme: Discovery Early Career Researcher Award. Field: 3101 - Biochemistry and Cell Biology. Lead: Dr Yun Shi