Hyperboloidal Curvature as a Novel Stem Cell Senescence Regulator. This project aims to understand how hyperboloidal curvature influences cell senescence and its underlying mechanisms in mesenchymal s
Description
Hyperboloidal Curvature as a Novel Stem Cell Senescence Regulator. This project aims to understand how hyperboloidal curvature influences cell senescence and its underlying mechanisms in mesenchymal stem cells. Hyperboloidal curvature plays a significant role in deciding normal stem cells' behaviour and function. Yet, the impact of these hyperboloidal curvatures on senescent stem cells remains to be explored. The project will bring together complementary expertise by combining biomaterial, cell and molecular biology, and engineering to gain an in-depth understanding of the underlying mechanisms of cellular senescence and rejuvenation. The anticipated outcomes will strengthen Australia’s research capacity and generate new knowledge of significance for our fundamental understanding of cellular senescence. . Scheme: Discovery Projects. Field: 4003 - Biomedical Engineering. Lead: Prof Hala Zreiqat