New treatments for animal infections, an economic and health imperative. Food security is critical to human social and economic wellbeing. Access to protein (and meat), is considered essential. Despit

Description

New treatments for animal infections, an economic and health imperative. Food security is critical to human social and economic wellbeing. Access to protein (and meat), is considered essential. Despite being major sources of protein 98% of Australia’s commercial chicken flocks are infected with Eimeria; high levels are also found in ruminants. More concerning is the high rates of Toxoplasmosis gondii (T. gondii) in ruminants. Infectious to humans by a faecal-oral route from cats and ingestion of undercooked meat, it can result in blindness, severe lung and brain disease, even death mostly in the pregnant and immunocompromised. Once infected there is no treatment or cure. Our novel compounds are capable of killing both Eimeria and T. gondii parasites. This program will see their development as veterinary drugs.. Scheme: Linkage Projects. Field: 3404 - Medicinal and Biomolecular Chemistry. Lead: Prof Adam McCluskey