Materials to cross gastrointestinal barrier and escape liver metabolism. This project aims to engineer advanced hybrid materials to cross the gut barrier and escape liver metabolism by utilising a nov

Description

Materials to cross gastrointestinal barrier and escape liver metabolism. This project aims to engineer advanced hybrid materials to cross the gut barrier and escape liver metabolism by utilising a novel multifunctional polymeric microcapsule to encapsulate and protect nanoparticles with tailored mechanical properties and bio-coating. It expects to generate significant new knowledge on the role of nanomaterial’s properties and bio-coating in its capability to go across intestinal wall and evade liver clearance, eventually leading to the development of advanced materials for targeted delivery via oral administration. Expected outcomes include patented technologies and next-generation oral delivery systems that are likely to benefit veterinary, food and pharmaceutical sectors where delivery technology is applied. . Scheme: ARC Future Fellowships. Field: 4004 - Chemical Engineering. Lead: Prof Hang Ta