Revealing the role of gut-bacterial amyloids in human ageing. The biology of ageing is dependent on various biochemical processes. Recent evidence suggests that gut-bacteria can influence these ageing

Description

Revealing the role of gut-bacterial amyloids in human ageing. The biology of ageing is dependent on various biochemical processes. Recent evidence suggests that gut-bacteria can influence these ageing-associated processes, in turn impacting the quality of ageing and productivity in later stages of life. This project aims to investigate how components from microbial biofilms, termed amyloids, leach out from the gut, access other tissues and interfere with cellular and molecular processes involved in ageing. It will generate new knowledge on ageing biology in relation to gut-bacteria. Expected outcomes include conceptual insights in gut-microbiome-human communications with social benefits to improve the quality of ageing in senior citizens and Australia’ economic capacity in aged-care services.. Scheme: Discovery Early Career Researcher Award. Field: 3404 - Medicinal and Biomolecular Chemistry. Lead: Dr Ibrahim Javed