Mechanisms of bacterial adaptation: from persistence to innovation. This research aims to use frontline structural and molecular biology approaches to uncover the mechanisms of bacterial adaptation. I

Description

Mechanisms of bacterial adaptation: from persistence to innovation. This research aims to use frontline structural and molecular biology approaches to uncover the mechanisms of bacterial adaptation. It seeks to advance fundamental knowledge of autotransporters (ATs), the largest family of secreted bacterial proteins that drive biofilm formation, host invasion, and antibiotic resistance—processes essential for bacterial survival. Expected outcomes include elucidating the structural basis of ATs' multifaceted functions and harnessing their potential to develop innovations such as intracellular delivery systems for bioactive molecules. This could inform future infection control strategies and lead to biotechnological tools, benefiting key industry sectors including agriculture, food production, and healthcare.. Scheme: Discovery Projects. Field: 3101 - Biochemistry and Cell Biology. Lead: Prof Begoña Heras