How Does Ageing Affect GPCR Signalling: Focusing on Pro-resolving Receptors. G-protein-coupled receptors (GPCRs) are evolutionarily conserved cell surface proteins crucial for regulating human and ani

Description

How Does Ageing Affect GPCR Signalling: Focusing on Pro-resolving Receptors. G-protein-coupled receptors (GPCRs) are evolutionarily conserved cell surface proteins crucial for regulating human and animal physiology by transmitting signals essential for growth and ageing. This project aims to unravel the molecular mechanisms underlying GPCR-mediated signalling in physiological ageing, utilizing state-of-the-art experimental methods and multi-omics platforms. By exploring GPCR-driven cellular biology and dynamics in both 'young' and 'aged' systems, the project seeks to transform our understanding of mammalian ageing. The outcomes will advance biological knowledge, foster interdisciplinary collaborations, and promote cutting-edge research training, placing Australia at the forefront of global life sciences innovation. . Scheme: ARC Future Fellowships. Field: 3214 - Pharmacology and Pharmaceutical Sciences. Lead: Dr Chengxue Qin