What makes a memory? Identifying learning molecules in a simple brain. This proposal aims to dissect the minimal chemical requirements for learning and memory formation in the compact, experimentally-

Description

What makes a memory? Identifying learning molecules in a simple brain. This proposal aims to dissect the minimal chemical requirements for learning and memory formation in the compact, experimentally-accessible nematode brain. It seeks to advance molecular neuroscience and psychology using an innovative proximity labelling approach, to identify proteins present specifically during learning within the brain of a living animal. In expected outcomes and benefits, the project will revealing the entire network of molecules required as memories are being formed, and will generate breakthrough knowledge of the key molecular pathways driving specific forms of memory in different parts of the nervous system. These findings are essential to understand more complex forms of learning and memory formation in bigger brains.. Scheme: Discovery Projects. Field: 3109 - Zoology. Lead: Dr Yee Lian Chew