A New Microbial Model to Study Phage Biology in the Gut. This project explores the biology of bacteriophages that reside within the gastrointestinal tract. We aim to understand the biology, molecular

Description

A New Microbial Model to Study Phage Biology in the Gut. This project explores the biology of bacteriophages that reside within the gastrointestinal tract. We aim to understand the biology, molecular mechanisms, and ecological impacts of prophages of the key bacterial gut symbiont, Bacteroides thetaiotaomicron. This is significant as bacteriophages play important roles in gut health and there is a substantial knowledge gap on phage biology and function within the gut. Expected outcomes include a new experimental microbial model system of the gut, and new molecular mechanisms and tools to manipulate gut bacteria. Outcomes from the project include high-impact publications, training of Australian scientists, and potential impacts on the biotechnology and microbiome sectors.. Scheme: Discovery Projects. Field: 3107 - Microbiology. Lead: Prof Jeremy Barr