Investigating how nuclear bodies may establish cellular memory. This project aims to determine how nuclear bodies establish cellular memory. This project expects to generate new knowledge in molecular

Description

Investigating how nuclear bodies may establish cellular memory. This project aims to determine how nuclear bodies establish cellular memory. This project expects to generate new knowledge in molecular programming of immune cells, by leveraging interdisciplinary collaborations and using cutting-edge high-resolution microscopy, gene and protein knockout systems, as well as cell and chromatin biology techniques. Expected outcomes include new principles of how cells are reprogrammed for enhanced function & the ability to adapt to microenvironmental change for long-term survival. This should provide significant benefits such as knowledge creation that may lead to development of technology to reprogram cell function across many species, as well as enhancing Australian research capacity and recognition.. Scheme: Discovery Projects. Field: 3204 - Immunology. Lead: Prof Kim Good-Jacobson