The mechanistic basis of how bacteria respond to environmental change. The bacterial cell surface is the primary barrier that protects from external threats; however, it remains unclear how bacteria r

Description

The mechanistic basis of how bacteria respond to environmental change. The bacterial cell surface is the primary barrier that protects from external threats; however, it remains unclear how bacteria rapidly remodel this protective layer. This project aims to discover the mechanisms by which bacteria rapidly respond to changes in their local environment. The project expects to define these mechanisms using combinations of molecular analysis, cutting-edge nanoscale imaging, genome-wide profiling and AI-driven structural analysis. Expected outcomes are to understand this fundamental biological principle and advance our knowledge of bacterial cell biology and environmental adaptation. The findings from this project should provide significant benefits for the global research community and commercial biotechnology.. Scheme: Discovery Early Career Researcher Award. Field: 3101 - Biochemistry and Cell Biology. Lead: Dr Thomas McLean