Tracing the epigenetic life-history of cells. Each cell of the human body contains identical genetic information that is activated in different ways to form varied cell types. This research aims to de

Description

Tracing the epigenetic life-history of cells. Each cell of the human body contains identical genetic information that is activated in different ways to form varied cell types. This research aims to develop novel single-cell genomic technologies to explain the origins of different cell types. This project expects to discover the molecular mechanisms through which specialised cell types are formed, which has been difficult to decipher using existing methods. My novel approach will elucidate how a small population of seemingly homogenous cells can give rise to a myriad of types of cells. Tracing the life histories of cells across time should lead to broad applications including in developmental biology, neuroscience and immunology.. Scheme: Discovery Early Career Researcher Award. Field: 3105 - Genetics. Lead: A/Prof Seth Cheetham