Grants & Opportunities

A Concurrent Multiscale Model for Improved Prediction of Drying Process. This project aims to develop an innovative multiscale model for food drying, which integrates spatial and temporal nonlinear behaviours at different scales. The proposed unifying theory will capture dynamic micro level features and upscale them to macro level features through a concurrent bridging scheme. As cellular elements critically govern the drying process, the fundamental understanding captured through this theory will lead to more accurate prediction of drying kinetics, deformation and quality changes, and hence the development of efficient drying systems. This project will overcome a longstanding research problem and position Australia at the forefront in world drying research to reap substantial economic benefits for Australia.. Scheme: Discovery Projects. Field: 0908 - Food Sciences. Lead: Prof Azharul Karim

Combating Antimicrobial Resistance with Bismuth, Gallium and Indium. This research project focuses on the design, development, and application of new bismuth, gallium and indium compounds as antimicrobial agents. These metals act as iron mimics in vivo and can exert antimicrobial activity while displaying low systemic toxicity in humans. The project aims to exploit this, and the inability of microbes to easily develop resistance towards metals, to combat bacteria for which modern drugs are rapidly becoming ineffective, as highlighted in the WHO and US Centre for Disease Control list of critical and priority pathogens. The intended outcome is that efficacy will be driven through advances in synthetic and structural chemistry, discovering the mode of action, and creating anti-infective coatings and hydrogels.. Scheme: Discovery Projects. Field: 0302 - Inorganic Chemistry. Lead: Prof Philip Andrews

A systems materials engineering strategy for hybrid ion capacitors. This project aims to develop a data science-driven approach to allow the use of materials systems engineering strategy to quantify the cell-level design of electrochemical energy storage devices such as hybrid ion capacitors. The intended outcomes of this project include new dynamic equivalent circuit models and a new quantitative approach to make the electrodes pairing predictable and realise their optimal design against the needs of the specific applications. It will also demonstrate a combined strategy of data science and discipline-specific experiments and theories to advance the emerging field of materials systems engineering. . Scheme: Discovery Projects. Field: 0912 - Materials Engineering. Lead: Prof Dan Li

Impacts of diet on the brain, body, and microbiome. Dietary habits determine cognitive function, metabolism and the composition of the gut microbiome. This project seeks to clarify the role of the gut microbiome in diet-induced changes to cognition. It aims to do so through longitudinal studies of cognitive function in which dietary patterns are systematically varied, and intervention studies where cognition is tested after experimentally manipulating the gut microbiome. Expected outcomes include new interdisciplinary knowledge spanning psychology, neuroscience, nutrition and metabolism. This project is timely given the enormous shifts in Australian dietary choices. The knowledge to be gained should provide benefits to individual and public health, agriculture, and food systems.. Scheme: Discovery Projects. Field: 1701 - Psychology. Lead: Dr Michael Kendig

Developing novel two-dimensional hybrid nanostructures for renewable energy. This project aims to develop novel two-dimensional (2D) hybrid nanostructures with new physical and chemical properties. This innovation intends to address the critical challenges of control functionalisation of 2D hybrid nanostructures: essential to understanding the potential of nanomaterials in key applications of energy generation. Expected outcomes include scalable technology to produce functional 2D nanomaterials and hybrid nanostructures to accelerate research to advanced materials and frontier material manufacturing technologies. This project will provide significant social and economic benefits to Australia in the growth of sectors in advanced materials, energy generation, and advanced manufacturing.. Scheme: Discovery Projects. Field: 0912 - Materials Engineering. Lead: Prof Weiwei Lei

Advancing the Science of Giant Planet Atmospheric Entry. This project aims to improve models used to design the heat shields which protect probes entering the atmospheres of the giant planets - four gaseous planets out beyond Mars. Further giant planet exploration is a key planetary science goal of the coming decade. However, the environment which an entry probe would experience features many unknowns and large uncertainties, making a mission a risky undertaking. Using unique experimental capabilities and state-of-the-art modelling, the expected project outcome is experimentally validated giant planet entry flow and surface chemistry models. This will allow more efficient heat shields to be designed while also increasing the chance of mission success, furthering our understanding of the universe.. Scheme: Discovery Projects. Field: 0901 - Aerospace Engineering. Lead: Prof Richard Morgan

Sensing and Communications for Tactical Radio: Mapping the RF Weather. This project investigates sensing, localisation and communication strategies to improve the performance of modern tactical radio networks. Such networks face all of the well-known design challenges of mobile ad-hoc networks (MANETs) but with added complication of a contested and adversarial operating environment. By exploiting the power of radio nodes to sense the radio spectrum, as well as to communicate over it, a distributed network of nodes can create a detailed picture of the surrounding radio-frequency (RF) environment: the nodes can work together to map the “RF weather”. In this project we will design advanced sensing and localisation methods to accurately map the RF spectrum, and then exploit this map in communication system design.. Scheme: Discovery Projects. Field: 1005 - Communications Technologies. Lead: Prof Jamie Evans

Large Scale Natural Convection Boundary Layers with Non-Boussinesq Effects. This proposal aims to understand and predict heat transfer by turbulent natural convection in two scenarios, firstly at very large environmental scales, such as occur on melting Antarctic ice sheets, and secondly convection involving very large temperature differences such as occur in solar thermal power plants and industrial processes. These natural convection flow regimes are incredibly difficult to investigate directly but by focusing on the fundamental dynamics of the turbulent flows using large scale numerical simulations and innovative experiments, the project is expected to develop better analytical and computational models which will underpin improvements in global ocean models and improve energy efficiency.. Scheme: Discovery Projects. Field: 0915 - Interdisciplinary Engineering. Lead: Prof Steven Armfield

Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lipid biology at the cellular and sub-cellular level across a wide range of in vitro and in vivo models. The outcomes of this project should provide significant knowledge to tackle modern societal challenges in healthy ageing, brain pathologies and neurodegenerative diseases.. Scheme: Discovery Projects. Field: 0399 - Other Chemical Sciences. Lead: A/Prof Mark Hackett

Enhancing and evaluating stakeholder engagement for improved water outcomes. Stakeholder engagement, widely recognised as essential in successful water governance, remains ad hoc both in practice and as a research theme. Using a detailed analysis of a complex evolutionary case of stakeholder engagement in water management in the Murray-Darling Basin (1900- 2020), this project aims to develop new approaches to measure the structure and form of socio-culturally derived stakeholder engagement system, to improve socio-economic and environmental benefits from water. The expected output is a new diagnostic tool for evaluating stakeholder engagement that can be taken up by governing bodies. The expected benefit is more inclusive, equal, and adaptive water governance through more effective stakeholder engagement.. Scheme: Discovery Projects. Field: 0502 - Environmental Science and Management. Lead: Prof Yongping Wei

Cold catalysis for water splitting. This project aims to develop photocatalysts via AC magnetic field through nanoscale heating for efficient H2 generation. This project is to introduce cold catalysis concept, which heats catalysts only but not solution, thus called cold catalysis, in the area of production of renewable energy. Expected outcome is the creation of clean and low cost catalysts to effectively harvest the chemical energy from the sun via splitting of water into H2 and O2 without causing any environmental damage. This unique technology will also help to address clean energy generation, which is in line with H2 economy plan by Australia government, and provide opportunities for new industries that will benefit Australian economy.. Scheme: Discovery Projects. Field: 0912 - Materials Engineering. Lead: Dr Jae-Hun Yang

Artificial Intelligence, Robots, and Agriculture: Social and ethical issues. This project aims to investigate the social and ethical issues raised by the use of artificial intelligence and robotics in agriculture. By combining social science research methods and philosophical analysis, the project aims to generate new knowledge in bioethics and applied ethics. Expected outcomes of this project include an account of the social and ethical issues farmers, rural communities, and consumers anticipate arising from these technologies, improved understanding of these issues, and an account of how these groups would like to see these issues addressed. This should help Australia benefit from the responsible use of artificial intelligence and robotics in agriculture.. Scheme: Discovery Projects. Field: 2201 - Applied Ethics. Lead: Prof Robert Sparrow

Pursuing Public Health in The Preindustrial World, 1100-1800. This project aims to recover community-health practices in three world regions before the takeoff of European industrialization. It challenges a common chronology and geography in public health history by examining how especially non-urban societies in Europe, the Middle East and India adjusted their behaviors and environments to manage health risks, often relying on the principles of humoral (or Galenic) medicine. A multidisciplinary team will conduct spatial, material, pictorial and text-based analyses, which will collectively extricate public health from Eurocentric narratives of modernization and illuminate preventative-medical cultures often ignored or studied in isolation.. Scheme: Discovery Projects. Field: 2202 - History and Philosophy of Specific Fields. Lead: Prof Dr Guy Geltner

Micro-electrofluidic platforms for monitoring 3D human biological models. The ability to study living cells and human biological models (cell cultures) delivers greater understanding of basic biological function and response to applied (bio)chemical stimuli. Creating the physical environments to sustain biological models, and mimic natural conditions and fluidic pathways, is immensely challenging, yet essential to deliver meaningful observational data. This project will deliver this capability through the convergence of expertise and innovation in analytical chemistry, materials science and cellular biology, ultilising the latest technology and understanding of 3D micro/electrofluidics, to enable the study and stimulation of advanced biological models, sustained within precisely controlled 3D micro-environments.. Scheme: Discovery Projects. Field: 0903 - Biomedical Engineering. Lead: Prof Brett Paull

Functional identification of vaccine targets in pathogenic mycoplasmas. Mycoplasmas are important bacterial pathogens in domestic animals that are incompletely controlled by current vaccines. As a result current control measures for the diseases they cause rely on ongoing treatment with antibiotics. This project will aim to use functional genomics and metabolomics to determine the function of specific surface proteins of a model mycoplasma to identify targets for novel approaches to vaccines against these pathogens, and to then assess the potential for inclusion of these proteins in vaccines. Ultimately this will lead to improved vaccines against these important pathogens, improving agricultural productivity and reducing the use of antibiotics in intensively raised livestock.. Scheme: Discovery Projects. Field: 0707 - Veterinary Sciences. Lead: Prof Glenn Browning

Modelling dynamics in spatial ecology. This project addresses how birth, death and movement drive patterns of plants and animals in space and time. We aim to apply and extend dynamical statistical models grounded in theory. Dynamical models are needed for us to understand how species and ecological communities respond to environmental change and disturbance including bushfires, climate change and extremes and species invasion. Using data from forest plots and animal movement, we aim to understand influences on individuals and species, and how to use that to generate robust predictions. The project is expected to produce statistical models and software for use by ecologists. This should help predict, and manage, ecological impacts of environmental change and disturbances.. Scheme: Discovery Projects. Field: 0502 - Environmental Science and Management. Lead: Prof Peter Vesk

Is there a climatic tipping point for Antarctic Bottom Water formation? Antarctic Bottom Water plays an important role in global ocean circulation and climate and yet its formation is also highly sensitive to climate change. This project will analyse new seafloor, core and water samples from the understudied Cape Darnley, East Antarctica, collected on a voyage in early 2022. This new data will be used in combination with an improved high resolution regional ocean model, to understand modern and past Antarctic Bottom Water formation under different climate states (warmer and colder than present), to determine if there are climate tipping points for the shut down of Antarctic Bottom Water formation. The anticipated benefits include a better understanding of future climate change on this important water mass.. Scheme: Discovery Projects. Field: 0405 - Oceanography. Lead: Prof Helen Bostock

Elucidating the molecular basis of plant potyvirus resistance . Plant viruses are responsible for a large proportion of crop losses, and genetic resistance is currently the most effective means to control viral spread. This project investigates, on a molecular and structural level, host factors that plant viruses hijack during infection, and in particular, the mutations in these factors that confer resistance. We further aim to elucidate the mechanisms by which plant viruses overcome resistance mediated by these host factors. A detailed understanding of the molecular interactions between plant viruses and their host will enable new, robust and more effective forms of resistance to be engineered. This work therefore has economic and environmental implications for agricultural productivity in Australia. . Scheme: Discovery Projects. Field: 0601 - Biochemistry and Cell Biology. Lead: Dr Mary Christie

Corrosion of heat resisting alloys in steam/hydrogen-rich environment . Hydrogen is a clean fuel for energy future. Its production and utilisation unavoidably involve water vapour and hydrogen at high temperature which is however corrosive to materials used in the system. This project aims to investigate corrosion behaviour of heat resistant alloys in the presence of both hydrogen and water vapour, mechanisms of water transport in oxide scale, and the effect of hydrogen on water vapour corrosion. Alloying effects on corrosion rates will be defined and methods of slowing or preventing water vapour corrosion in the presence of hydrogen will be devised. The results will provide a basis for improved design/selection of heat resisting alloys for hydrogen production and hydrogen utilisation industries.. Scheme: Discovery Projects. Field: 0912 - Materials Engineering. Lead: Prof Jianqiang Zhang

Network activity and the role of NMDA receptors in associative learning. The brain is the most complex machine we know, and its activity shapes every aspect our lives. Studies over decades using tools from molecular and cellular neuroscience and behavioural experiments have discovered the parts of the brain involved in learning and memory formation. Much is understood about the neural circuits that mediate learning but how memories are formed and stored are not understood. The aim of this project is to understand learning and memory formation using a simple Pavlovian learning paradigm, fear conditioning. Using cutting-edge molecular tools we will label the circuits in the amygdala that mediate this learning and the nature of the memory trace. In the long term, these results may drive novel storage devices.. Scheme: Discovery Projects. Field: 1109 - Neurosciences. Lead: Prof Pankaj Sah

The impact of female sex hormones on neurodevelopment. This project aims to characterise the contribution of sex hormones to the development of emotional brain circuits in female adolescents. Puberty is associated with profound changes in emotional behaviours in females, but we know little about the underlying brain mechanisms. In particular, research has neglected to consider the role of the sex hormones for which changes are a defining feature of female puberty (eg, oestradiol). This work will be the first to comprehensively advance our understanding of the unique role of sex hormones in shaping the adolescent female brain. It will provide critical understanding of how individual differences in hormonal factors increase risk for emotional problems in females, and inform treatment strategies.. Scheme: Discovery Projects. Field: 1701 - Psychology. Lead: Prof Sarah Whittle

Turning crises into opportunities: Learning from high growth businesses. Being able to adapt and respond to crises such as the COVID-19 pandemic or bushfires is important for Australia's economic development. This project investigates how crises can be turned into opportunities. It analyses the strategic crises responses of business ventures that managed to defy the odds and to achieve high growth because of crises. The outcomes include an improved understanding of the opportunities crises present; and actionable, empirically grounded insights into successful crises responses. As such, the project will make significant contributions to core areas of entrepreneurship and management research. It will also help policymakers and entrepreneurs to improve economic resilience and to foster sustainable economic growth.. Scheme: Discovery Projects. Field: 1503 - Business and Management. Lead: A/Prof Frederik von Briel

Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.. Scheme: Discovery Projects. Field: 1103 - Clinical Sciences. Lead: Prof David Reutens

Rhizosphere mediation of soil greenhouse gas fluxes with climate change. Increasingly extreme heat waves, droughts and floods contribute major uncertainties in predicting natural land-based climate change mitigation. This project will quantify current and future greenhouse gas absorption in a managed grassland ecosystem, and the new knowledge will contribute to carbon emissions offsets in climate change accounting schemes. We will conduct this research using a manipulative field experiment, controlled laboratory incubations, microbial gene analysis and mechanistic modelling to provide new insights into future potential climate change mitigation by soils.. Scheme: Discovery Projects. Field: 0501 - Ecological Applications. Lead: Prof Elise Pendall

Microbially induced calcium carbonate precipitation in different substrates. Carbonates in the form of limestone represent an important reservoir of carbon on earth. They are recorded in several natural geological formations as corals, stromatolites, beach rocks. Microbes play an important role in the formation as well as dissolution of carbonates during microbially induced calcium carbonate precipitation (MICP) reactions on different substrates in natural and built environments. Much of our knowledge on MICP is limited due to poor understanding of the reaction kinetics at a molecular level. This project will develop new methods to enable and advance the knowledge of MICP process with profound implications for understanding natural geological formations as well as widen the scope of current engineering applications.. Scheme: Discovery Projects. Field: 0402 - Geochemistry. Lead: Dr Navdeep Dhami